marginalianoun
notes written in the margins; peripheral commentary;


[marginalium]

"What We Got Wrong About Depression and its Treatment"

26 Jun 2024

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Some new, some old, observations about the mismanagement of depression. Good just for the highlights. Full paper here:

Depression is neither disease nor disorder rather an adaptation that evolved to serve a purpose

Depression is so much more prevalent than currently recognized that it is “species typical”

Antidepressants drive neurotransmitter levels so high that homeostatic regulation kicks in

Antidepressants may suppress symptoms in a manner that increases risk for subsequent relapse

Cognitive therapy works by making rumination more efficient and “unsticking” self-blame

Adding antidepressants may interfere with any enduring effect that cognitive therapy may have


Anthologies: Gratification, Somatic Architecture, On (Un)happiness, Neurotypica, Karstica

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More about Dorian Minors' project btrmt.

btrmt. (text-only version)

The full site with interactive features is available at btr.mt.

btrmt. (betterment) examines ideologies worth choosing. Created by Dorian Minors—Cambridge PhD in cognitive neuroscience, Associate Professor at Royal Military Academy Sandhurst. Core philosophy: humans are animals first, with automatic patterns shaped for us, not by us. Better to examine and choose.

Core concepts. Animals First: automatic patterns of thought and action, but our greatest capacity is nurture. Half Awake: deadened by systems that narrow rather than expand potential. Karstica: unexamined ideologies (hidden sinkholes beneath). Credenda: belief systems we should choose deliberately.

The manifesto. Cynosure (focus): betterment, gratification, connection. Architecture (support): inner (somatic, spiritual, thought) and outer (digital, collective, wealth).

Mission. Not answers but examination. Break academic gatekeeping. Make sciences of mind accessible. Question rather than prescribe.

Writing style. Scholarly without jargon barriers. Philosophical yet practical—grounded in neuroscience and lived experience. Reflective, discovery-oriented. Literary references and metaphor. Critical of systems that narrow human potential. Rejects "humans are flawed"—we're half awake, not broken.

Copyright. BTRMT LIMITED (England/Wales no. 13755561) 2026. Dorian Minors 2026.

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About Dorian Minors. Started btrmt. in 2013 to share sciences of mind with people who weren't studying them. Background: six years Australian Defence Force (Platoon Commander, Infantry); Gates Cambridge Scholar; PhD cognitive neuroscience, University of Cambridge (2018-2024); currently Associate Professor, Royal Military Academy Sandhurst. Research interests: neural basis of intelligent behaviour, decision intelligence, ritual formation/breakdown, ethical leadership, wellbeing.

External projects (links also available via Analects):